N.I.E. stands for National Intelligence Estimate. It is the term paper, if you will, of our N.I.C., which stands for National Intelligence Council, on some subject.
In this case, the subject is Iran's nuclear intentions (PDF)
The N.I.E. contradicts the president Bush and his bluster regarding Iran so the republican response is twofold Blame the messenger and Keep up the pressure
Do these misguided liars aspire to make of our world a throne of ashes?
When does Ms. Pelosi expect to take up the responsibility associated with her office?